Jin Xie

Projects

Ferritin caged molecules for photodynamic therapy and drug delivery

Posted DateJune 12, 2018
Technology SummaryNanoparticle-based drugs are emerging as an important class of therapeutics. Nine nanoparticle drugs have received regulatory approval for the treatment of various cancers. These include Doxil and ABI-007 that have entered mainstream of cancer management in the clinic. Unlike conve...
received regulatory approval relative leakiness compared red blood cells/platelets includes vessel collapse rgd modified ferritin

Gd-encapsulated carbonaceous dots for fluorescence/MRI dually modal imaging

Posted DateNov. 14, 2016
Carbon Encapsulated Gadolinium Contrast AgentsGd-based complexes have been widely used as contrast agents for magnetic resonance imaging (MRI). However, these complexes have been found to induce nephrogenic systemic fibrosis in patients with renal diseases. We have developed a Gd-based biologically ...
magnetic resonance imaging commonly recognized threshold superior r1 relaxivity highly photostable photoluminescence real-time mr imaging

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