Technologies

OH-FD22 Cell Adapted Porcine Deltacoronavirus (PDCoV) Strain

Technology description

Porcine deltacoronavirus (PDCoV) is a novel coronavirus that causes diarrhea in nursing piglets. In extreme cases, these piglets died following infection. PDCoV is similar to other transmissible viruses in porcine populations, but is not transmissible to humans. Following its first detection in the United States (US) in February 2014, additional PDCoV strains have been identified in the US and Canada. A real-time RT-PCR has been developed by Marthaleret al.to detect PDCoV and has been used to diagnose PDCoV field infections. However, other virological and serological diagnostic assays are lacking. A critical step to develop PDCoV diagnostic assays and potential future vaccines is the isolation of PDCoV in cell culture.

Researchers at The Ohio State University have described the cell culture isolation, serial propagation, and genetic characterization of the cell adapted PDCoV strains from a diarrheic pig. The information presented in this study is important for the development of diagnostic reagents, assays and potential vaccines against the emergent PDCoV strains.

This invention details the virus isolate that has been developed from methods derived at The Ohio State University.

由于技术保密工作限制,技术信息无法完全展现,请通过邮箱或短信联系我们,获取更多技术资料。

More information

Categories
  • Information technology
  • Infectious Department
  • Respiratory medicine
Keywords:

ohio state university

potential future vaccines

additional pdcov strains

emergent pdcov strains

serological diagnostic assays

下载 PDF 文档


感兴趣

Contact us

知繁业茂-yintrust logo知繁业茂-Branchly Innovation logo 知繁业茂-autmasia logo迈科技 logo