Jan. 15, 2010
Technology Summary:Provides a method and apparatus to measure intracranial pressure in a non-invasive way, using images of the eye.
Brain trauma and other neurological conditions, including brain tumors, can cause elevated ICP. This elevated pressure can be fatal if prolonged, so it must be monitored and treated.
Currently, ICP is usually measured with a spinal tap, which involves puncturing the subarachnoid space of the spinal cord. For many diseases, this must be done repeatedly to monitor treatment results or disease progression. Such invasive monitoring involves risk and discomfort and is not always feasible.
This technology measures ICP in a simpler, non-invasive and far less-painful way. It would benefit the 375,000 Americans who are hospitalized annually with non-fatal brain injuries.Technology Description:Provides a non-invasive method for measuring ICP by imaging the patient’s eye with Optical Coherence Tomography (OCT).
Obtains an approximation of ICP by using OCT images to monitor changes of the optic nerve head. Elevated ICP causes the optic nerve head to swell.
OCT can detect the preclinical signs of this swelling, called papilledema. These signs are dependent on relative ICP and intraocular pressure (IOP).Thus, ICP can be calculated by measuring the preclinical signs of papilledema, using OCT combined with IOP measurements.
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optical coherence tomography
optic nerve head
non-fatal brain injuries
monitor treatment results
measure intracranial pressure
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