Technologies

Technical Summary

Emory University researchers have developed software to increase the efficiency of electrophysiological experiments. “EasyOocyte” runs commercially available digitizing boards and rotary valves. The software helps convert a fluctuating voltage from an amplifier into a digital record for analysis. The user may enter a protocol, in relation to valves, timing, and membrane potential, which the program executes to perfuse different drugs onto a Xenopus oocyte that has been injected with RNA of a target protein and is subject to voltage clamp. This software allows the automation of pharmacological experiments and increased research efficiency.