May 23, 2019
Delayed cerebral ischemia (DCI) and continued bleeding are the most common causes of death and disability in patients who have suffered aneurysmal subarachnoid hemorrhage (aSAH). aSAH is a life-threatening type of stroke that occurs when an aneurysm (blood vessel burst) leads to bleeding in the space surrounding the brain. DCI in particular occurs in up to 46% of aSAH cases, and is largely due to vasospasm and reduced blood flow in the affected area. As many as 1/3 of patients die following aSAH, while another 1/3 are left with life-altering disabilities. Despite its prevalence and severity, there is no standardized method for identifying patients at risk of DCI post-aSAH.
To improve patient outcomes, researchers at USC have developed a novel method for assessing DCI risk from analysis of standard blood-brain barrier (BBB) permeability imaging. Here, BBB permeability is determined from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and the level of dysfunction is directly correlated with a DCI risk level. In small-scale patient studies, researchers have shown that the BBB permeability levels are indeed distinct enough to successfully predict DCI, which allows patients to receive prompt life-saving care.
Assessment of patients post-stroke
由于技术保密工作限制，技术信息无法完全展现，请通过邮箱或短信联系我们，获取更多技术资料。
blood vessel burst
reduced blood flow
improve patient outcomes
standard blood-brain barrier
small-scale patient studies
B5, No.1600, North Guoquan Rd, Yangpu, Shanghai
info@yintrust.com
021-65679356
Premium