Technologies

Systemic Lupus Erythematosus is an autoimmune disease which affects many organs and has a wide range of clinical manifestations. The disease is characterized by joint pain, rashes, and fevers, as well as inflammation of organs including the heart, lungs and kidneys. The cause of lupus has been difficult to identify, as almost every pathway of the immune system is abnormal in effected individuals. The production of auto-antibodies is thought to be largely responsible for the observed pathology; however, there is recent evidence that T lymphocytes promote and mediate the progression of the disease.