Technologies

The present invention relates to an anti-cell aging composition containing an active ingredient of diheprolactone [(-)-loliolide]. Doxorubicin-based composition capable of inhibiting fibroblast age and replication aging are provided. Di-heparin [(-)-loliolide] was isolated from the extract of Polygoni avicularis herba. By inhibiting the aging of human fibroblasts, aging-related diseases such as skin aging, rheumatoid arthritis, osteoarthritis, hepatitis, chronic skin lesions, arteriosclerosis, prostatic hyperplasia and liver cancer can be effectively treated.