May 30, 2013
Transdermal delivery of medications and other compounds has been aggressively pursued for many decades. Although patches have been used to deliver small hydrophobic molecules such as nicotine and nitroglycerin, an external pressure source in conjunction with a direct subcutaneous access port are required to deliver the majority of therapeutically important drugs through the skin. Microfluidics has played an important role in this area by providing microneedle arrays and miniature pumps. Although microneedle arrays made of silicon, polymers, and metals have reached a high degree of maturity in the past decade, their application has been limited due to the lack of a suitable micropump with adequate flow rate and back pressure.
Purdue University researchers have developed a new type of pump for drug-delivery patches that would use arrays of microneedles to deliver a wider range of medications possible than with conventional patches. The pump contains a liquid that boils at body temperature so that the heat from a finger's touch causes it to rapidly turn into a vapor, exerting enough pressure to dispense the drug through the microneedles. This technology's low-cost and battery-less operation make it the ideal single-use disposable transdermal drug dispenser.
由于技术保密工作限制，技术信息无法完全展现，请通过邮箱或短信联系我们，获取更多技术资料。
background transdermal delivery
adequate flow rate
battery-less operation make
therapeutically important drugs
providing microneedle arrays
B5, No.1600, North Guoquan Rd, Yangpu, Shanghai
info@yintrust.com
021-65679356
Premium