Oct. 22, 2013
Unique compounds for use in cancer therapeutics.
Treatment involving these compounds have shown strong synergistic cytotoxicity on colon and pancreatic cancer cells that were relatively resistant to the treatment with FU alone. Such a combination could prove to be significantly more potent than previous treatment options and at a lower risk to the patient.
The search for effective cancer therapeutics remains a hot topic on modern healthcare’s’ agenda. Various treatments have emerged in the hopes of countering a wide variety of cancer types. Since 1957, 5-fluorouracil (FU) has been used as a chemotherapy reagent for colorectal, breast, pancreatic, and other types of cancers. Over time, many derivatives of FU and combination therapies with other drugs have been developed and tested for effectiveness. These derivatives and combinations have proven useful in numerous instances, but there are still many other tumor types that show very little response or even exhibit resistance to FU-related treatments. The search for improved anti-cancer regimens capable of treating cancer (in general), especially resistant cancer types, has continued ever since.
Researchers at the University of New Mexico have developed a unique combination of compounds for use in cancer therapeutics. Treatment involving these compounds have shown strong synergistic cytotoxicity on colon and pancreatic cancer cells that were relatively resistant to the treatment with FU alone. Such a combination could prove to be significantly more potent than previous treatment options and at a lower risk to the patient.
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