Technologies

Perfusion and Diffusion Mismatch MR Imaging of the Brain with Radial Acquisition (PENUMBRA)

Technology description

Application area

• Quantification of perfusion and diffusion for clinical imaging, for example:
• Ischemic penumbra in acute ischemic stroke
• Central nervous system tumors, cerebrovascular occlusive disease and Alzheimer's disease using the Bookend Technique Abdominal imaging in liver and kidney disease
• Spinal imaging in multiple sclerosis Lower extremity imaging in peripheral arterial disease

Advantages

• Simultaneous acquisition of perfusion- and diffusion-weighted images
• Improved spatial resolution Improved coverage, especially of large structures such as the spine
• Improved accuracy of time-based metrics, such as time-to-maximum and time-to-peak
• Reduction in cortical blooming artifacts that can make determination of cerebral perfusion unreliable
• Reduces total acquisition time from 10 or more minutes to less than two minutes
• Spatial resolution and slice location are identical between perfusion and diffusion images, which eliminates the need for a specially-trained technician to manually overlay images