June 24, 2014
The present invention is a novel intellectual property related to a formulation of over 110 off-patent compounds capable of treatment and prevention of multiple types of cancers. The unique intellectual property position not only gives us method claims but also composition of matter. Based on a customized HyperCyt and flow cytometry integrated high-throughput system, we have identified chemicals that induce intracellular vacuoles in both advanced, hormone-sensitive and hormone-refractory prostate cancer cell lines as well as non-prostate cancer cell lines. The ability of these agents to induce intracellular vacuoles is related to the induction of autophagy and ultimately causes cell death.
As is widely known, cancer is a serious health concern and is a leading cause of death in the United States. Our novel testing method has resulted in the discovery of over 110 different compounds used alone or in combination that are proven useful in the prevention and treatment of late-stage prostate cancer, and have strong implications in prevention and treatment of multiple other forms of cancer.
The present invention is a novel intellectual property related to a formulation of over 110 off-patent compounds capable of treatment and prevention of multiple types of cancers. The unique intellectual property position not only gives us method claims but also composition of matter. Based on a customized HyperCyt and flow cytometry integrated high-throughput system, we have identified chemicals that induce intracellular vacuoles in both advanced, hormone-sensitive and hormone-refractory prostate cancer cell lines as well as non-prostate cancer cell lines. The ability of these agents to induce intracellular vacuoles is related to the induction of autophagy and ultimately causes cell death.
As the technology-transfer and economic-development organization for the University of New Mexico, STC.UNM protects and commercializes technologies developed at the University of New Mexico (UNM) by filing patents and copyrights and transferring the technologies to the marketplace. We connect the business communication (companies, entrepreneurs and investors) to these UNM technologies for licensing opportunities and the creation of startup companies. Visit www.stc.unm.edu.
Identifying new targets and methods of cancer prevention and treatment are critical to alleviate the enormous burden cancer presents. This novel testing and compositions shows promise for prevention and treatment of numerous forms of cancer, either as independent agents for therapy or in combination with established therapies, such as radiation treatment.
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induce intracellular vacuoles
intellectual property related
commercializes technologies developed
late-stage prostate cancer
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