Technologies

This technology is able to improve in particular:

• Fluorescence microscopes, Laserscanners, Raman Systems, STED and Localization Microscopes.
• Optical Accessories and Devices: Flowzytometer, Mikroarrayreader, Spectrometer

The novel construction of the object directly attached to the objective head instead of to the microscope body improves the following critical issues present in microscopes:

1. Less impact of external oscillations to the focusing unit: At an inverse microscope the focusing unit usually is at the object revolver attachment and at an upright microscope it is in the stage attachment. Both, object and revolver attachment as well as table construction typically have massive designs and are therefore susceptible to external oscillations.
2. Protection against collision of the objective: Micro-objectives typically exhibit a collision protection mechanism which causes mechanical tolerances between the focus and the objective turret.
3. Reduction of the distance between object and focal plane: Due to a shorter distance between object and focal plane the mechanical pathways are minimized decreasing the thermal impact and drift effects. The result can be even more improved by carefully selecting the particular material involved. The proposed device for image stabilization in microscopes can be mounted to all available standard microscopes.
4. Due to the new and simple object holder technique the high-resolution microscopes can obtain almost oscillation- and drift-free images under regular laboratory conditions. This fact is in particular of advantage for long time observations very often disturbed by drift effects or oscillations. The improved image recording spares the requirement of time consuming and tedious post processing of image data.