Methods of Treating and Diagnosing Pulmonary Emphysema
Technology description
Cathepsin E is expressed in human lung tissue and is increased in smokers with emphysema
Cathepsin E is detectable in urine as well as in serum using ELISA and therefore is a good diagnostic marker as well as a therapeutic target for emphysema
Demonstrated increased Nox3 protein expression in smokers compared to nonsmokers and in patients with emphysema compared to people without emphysema
TLR4, Nox3, and Cathepsin E have not been previously implicated in the pathogenesis of emphysema or any other lung process
Nov. 23, 2013
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