Background:
There are expected to be 23,130 newly diagnosed cases of primary malignant brain and central nervous system tumors in the United States in 2013 with a survival rate of 33.5%. Above that there are 98,000 to 170,000 new cases of metastatic brain tumors each year with a survival rate of 2.4%. With these tumors accounting for over 580,350 deaths and 30% of the total cancer mortality rate, there is a definite need for improvement in cancer diagnostics and therapeutics to increase patient’s outcomes.
Invention:
The invention proposed here produces a simultaneous view of the real anatomy (real object) and computer-processed near-infrared (NIR) fluorescence (synthetic object). This process is referred to as Augmented Microscopy. Using gold-liposome markers, the augmented microscope is capable of displaying NIR images in real time, superimposed with anatomical images of the operative view. This device can be directly implemented as a medical technology improving surgical efficiency by helping guide surgical procedures, delivering therapies, and improving resection of tumors.
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primary malignant brain
increase patient’s outcomes
metastatic brain tumors
displaying nir images